Miguel R Abboud Selected Research

Sickle Hemoglobin

1/2022	Voxelotor for the treatment of sickle cell disease in pediatric patients.
1/2022	Safety and efficacy of voxelotor in pediatric patients with sickle cell disease aged 4 to 11 years.
1/2021	Effect of Poloxamer 188 vs Placebo on Painful Vaso-Occlusive Episodes in Children and Adults With Sickle Cell Disease: A Randomized Clinical Trial.
1/2019	A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease.
11/2013	A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease.
3/2006	Renal kallikrein: a risk marker for nephropathy in children with sickle cell disease.
1/2006	Radiographic predictors of neurocognitive functioning in pediatric Sickle Cell disease.

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Miguel R Abboud Research Topics

Disease

25	Sickle Cell Anemia (Hemoglobin S Disease) 01/2022 - 05/2004
9	Neoplasms (Cancer) 01/2022 - 12/2008
9	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/2021 - 09/2010
9	Stroke (Strokes) 06/2020 - 05/2004
5	Pain (Aches) 01/2021 - 07/2014
5	Acute Chest Syndrome 06/2020 - 01/2017
4	Thalassemia 01/2021 - 03/2006
3	Hemolysis 01/2022 - 01/2009
3	Infarction (Infarctions) 01/2020 - 10/2008
3	Thrombosis (Thrombus) 02/2016 - 10/2008
2	Anemia 01/2022 - 01/2019
2	Venous Thrombosis (Deep-Vein Thrombosis) 11/2021 - 12/2017
2	Infections 01/2020 - 12/2008
2	Cerebral Infarction 01/2020 - 01/2017
2	Hemorrhage 01/2019 - 02/2016
2	Iron Overload 01/2017 - 12/2010
1	Disease Progression 01/2022
1	Hypoxia (Hypoxemia) 01/2021
1	Bone Resorption 01/2021
1	Hyperbilirubinemia 01/2021
1	Bacteremia 01/2021
1	Virus Diseases (Viral Diseases) 01/2020
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2019
1	Necrosis 01/2019
1	Leukemia 01/2018
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2018
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/2017
1	Neutropenia 05/2017
1	Leukopenia 01/2017
1	Pneumococcal Infections 08/2015
1	Headache (Headaches) 07/2014
1	Fatigue 07/2014
1	Nausea 07/2014
1	Vomiting 07/2014
1	Abdominal Pain (Pain, Abdominal) 07/2014
1	Priapism 01/2014
1	Venous Thromboembolism 11/2011
1	Pancreatitis 09/2010
1	Sarcoma (Soft Tissue Sarcoma) 09/2010
1	Bone Neoplasms (Bone Cancer) 09/2010
1	Fasciculation (Fasciculations) 08/2010
1	Glucosephosphate Dehydrogenase Deficiency 03/2010
1	Hemolytic Anemia 01/2009
1	Atherosclerosis 01/2009

Drug/Important Bio-Agent (IBA)

9	Hydroxyurea (Hydrea)FDA LinkGeneric 06/2020 - 03/2006
7	Sickle HemoglobinIBA 01/2022 - 01/2006
3	voxelotorIBA 01/2022 - 01/2019
3	TicagrelorIBA 01/2021 - 01/2019
2	Penicillins (Penicillin)FDA Link 01/2021 - 01/2002
2	beta-Globins (beta Globin)IBA 01/2020 - 01/2017
2	Analgesics (Analgesic Drugs)IBA 10/2019 - 01/2019
2	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2019 - 02/2016
2	Hemoglobins (Hemoglobin)IBA 01/2019 - 10/2008
2	2,2-dimethylbutyric acidIBA 07/2014 - 11/2013
2	Fetal Hemoglobin (Hemoglobin F)IBA 07/2014 - 03/2010
2	GlobinsIBA 07/2014 - 11/2013
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2014 - 01/2009
2	Ferritins (Ferritin)IBA 11/2009 - 01/2008
1	venetoclaxIBA 01/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	Poloxamer (Poloxamer 407)IBA 01/2021
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020
1	Ifosfamide FDA LinkGeneric 01/2019
1	Etoposide (VP 16)FDA LinkGeneric 01/2019
1	Vincristine (Oncovin)FDA LinkGeneric 01/2018
1	Specific Granule DeficiencyIBA 05/2017
1	ChromatinIBA 05/2017
1	NucleosidesIBA 01/2017
1	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 01/2017
1	Chelating AgentsIBA 01/2017
1	2-mercaptopurineIBA 01/2017
1	Diphosphates (Pyrophosphates)IBA 01/2017
1	Prasugrel Hydrochloride FDA Link 02/2016
1	23-valent pneumococcal capsular polysaccharide vaccineIBA 08/2015
1	Conjugate VaccinesIBA 08/2015
1	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 08/2015
1	Methotrexate (Mexate)FDA LinkGeneric 08/2014
1	Volatile Fatty AcidsIBA 07/2014
1	Deferoxamine (Desferal)FDA LinkGeneric 12/2010
1	Deferasirox FDA Link 12/2010
1	Allopurinol (Remid)FDA LinkGeneric 09/2010
1	Asparaginase (Elspar)FDA Link 09/2010
1	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2010
1	IronIBA 11/2009
1	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 01/2009
1	Arginine (L-Arginine)FDA Link 01/2009
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2009
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2009

Therapy/Procedure

13	Therapeutics 11/2021 - 03/2006
4	Blood Transfusion (Blood Transfusions) 08/2011 - 05/2004
2	Erythrocyte Transfusion 01/2020 - 01/2017
2	Secondary Prevention 01/2020 - 01/2017
2	Palliative Care (Palliative Therapy) 10/2013 - 08/2011
2	Prostheses and Implants (Prosthesis) 09/2010 - 12/2008
2	Limb Salvage 09/2010 - 12/2008
1	Radiotherapy 02/2017
1	Stem Cell Transplantation 06/2011
1	Chelation Therapy (Therapy, Chelation) 12/2010
1	Hematopoietic Stem Cell Transplantation 12/2009